Reggaeton Hits 2016 presents tracks and remixes from Clase-A, Mr. Padi feat. Yamil, Big Booty, Baroh & Tutto Duran, Area 3 feat. Nicko Altain, Sistema, Felipe Romero feat. Alkimista, Ruben Castro & Fran Garzziak feat. Sergio Requena, Ramon de la Rosa, R-Nestinho feat. J.Cabas, J Mandly & Manu Sanchez, AG, David Ferrari, Jey Alex, Dj Gago feat. Ramon de la Rosa & The Original's, Kasio La Eminencia Ft. Jeycy Thefeta, Danny Flow & Don Dy, A-Sika & Felipe Romero Feat. Phi, Sergio Requena, Heri Santana & Nano Suarez ft. DJ Gago, Luima, Impacto Urbano, J. Gabri, Tisu Ft. Xenzia, Yero Company & RM ft. Leo Guisado, Taykell & Racyel, Enea Marchesini